A nationwide manhunt for Hank Venture leads to untold dangers and unexpected revelations, while The Monarch is literally out for Dr Venture's blood. An imposing evil from the past reemerges to wreak havoc on the Ventures, The Guild, and even the Monarch marriage—it will take friends and foes alike to restore the Ventures' world to order… or end it once and for all.
as Dr. Venture / Phantom Limb / Jonas Venture Jr. (voice)
as Brock Samson (voice)
as Dean Venture (voice)
as Dr. Mrs. The Monarch / Henchman 21 / Shoreleave / Billy Quizboy / Dermott / Red Mantle / Rose / Ward (voice)
as Hank Venture / The Monarch / Sgt. Hatred / Hunter Gathers / Pete White / Watch (voice)
as Mantilla (voice)
as Red Death / Daisy (voice)
as Snoopy (voice)
as Clayton / Seth / Tour Guide (voice)
as Bobbi St. Simone (voice)
as Jefferson Twilight / OSI Agent (voice)
as Nuno Blood / Additional Blackulas (voice)
as Dr. Orpheus (voice)
as Ben (voice)
as The Alchemist / Conductor / Houseless Guy (voice)
